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  1. #1
    Sik
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    Why couldnt it be us :(

    http://www.ctru.auckland.ac.nz/index...rvention-trial

    Our Addiction Research
    A trial of the effectiveness of e-cigarettes as an aid to smoking cessation.



    Rationale
    Most people find it difficult to succeed in quit attempts largely because of dependence on nicotine but also to non-nicotine sensory cues. Nicotine replacement therapy (NRT) doubles quit rates by making the transition to non-smoker less traumatic. Nevertheless, absolute long-term quit rates are low. A product that has potential as a cessation aid and with wider appeal than NRTs is the electronic cigarette. People buy them to help quit smoking, reduce cigarette consumption and costs, to relieve tobacco withdrawal symptoms or as a replacement for smoking. However, despite the claims of efficacy and popularity there is no evidence from trials of their efficacy on quitting and safety.

    Aims
    To evaluate the quitting efficacy, acceptability, and adverse effects of an e-cigarette, comparing active (16mg nicotine) with nicotine patch and placebo (0mg nicotine) e-cigarettes.

    Design
    A three arm parallel group randomised controlled trial. Participants will be randomised into either a group who will use active e-cigarette for 12 weeks after quitting, nicotine patches for 12 weeks or placebo e-cigarettes for 12 weeks. Quit rates will be assessed at 3 and 6 months after the quit date.

    Study Status
    This study is in set-up phase.

    Funding
    This study is funded by the Health Research Council of New Zealand.

    CTRU Contact
    Chris Bullen, Principal Investigator

    CTRU’s Role
    The CTRU was involved in all aspects of study development, design and securing funding for this trial. In addition the CTRU is responsible for trial co-ordination, data management, data analysis and reporting.

    Collaborators
    This study is being conducted in collaboration with:
    Health New Zealand, Christchurch, New Zealand
    Inspiring Ltd, Auckland New Zealand
    Current Vape: Variable Wattage mod, EPM Boge tanks, Something Fruity

  2. #2
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    NZ are heading the world in this area, thats for sure.
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  3. #3
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    Kiwis have been researching eCigs for a long time-at least 2 years that I can think of. I think the failure rate for NRTs comes in 70%.

    Agree -why couldnt it be us.!Just once couldnt rational open minded common sense prevail!

  4. #4
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    Seems NZ is way ahead on a number of thing than Australia. The NZ Government actualy seem to trust their people unlike the Australian Govenrment who thinks we are too stupid to make our own decisions and be responsible for them. Australia the luck country - Bullshit!

    NZ v Aust
    R18+ for video games v Nanny state
    Distilling alcohol v Nanny state
    Suppressors for firearms v Nanny state
    E-Cigs v Nanny state

    Just a few examples of how progressive the NZ Government is and how they respect the individual.

  5. #5
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    only one problem...... e-cigs are not an NRT product as such and to assess them on the same terms as NRT might set them up for failure.
    Yes they are an alternative to smoking and yes the user can CHOOSE to gradually lower their nicotine over time in real life circumstances... however to drop from 16mg/ml to not using an e-cig AT ALL at the end of 12 weeks could pose a problem for some as their crutch has been compleatly removed. The removal of the e-cig at the end of 12 weeks will also disqualify the test subject from using the e-cig without nicotine in times of need over the following 6 month period.

    The beauty of the e-cig is that even after quitting the nicotine people can still use the device without nicotine in times of need without returning to cigarettes or addictive substances and that is why they have such a unique place in the market.

    The terms of this study do not take this into account and IMHO set the participants up for failure as their only choices are to abstain from tobacco, NRTs and e-cigs OR to return to smoking. Under these circmstances my guess is e-cigs will prove to be no-more beneficial than NRT products and simply prove the health departments point that e-cigs are no more effective than current NRT products, they do not offer anything new to the market and are therefore an unnessesary and an unwelcome introduction to the current market.

    While I applaud testing I find it hard not to veiw this study as heavily biased against the e-cig as it compleatly ignores the fact that the e-cig offers something that no exisiting NRT product does, and that is a FAILSAFE in times of need without returning to cigarettes or addictive substances.
    Last edited by GirlyPantz; 25-05-11 at 05:24 PM.

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    You make some very good points there GirlyPanz-

  7. #7
    Sik
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    Quote Originally Posted by GirlyPantz View Post
    only one problem...... e-cigs are not an NRT product as such and to assess them on the same terms as NRT might set them up for failure.
    Yes they are an alternative to smoking and yes the user can CHOOSE to gradually lower their nicotine over time in real life circumstances... however to drop from 16mg/ml to not using an e-cig AT ALL at the end of 12 weeks could pose a problem for some as their crutch has been compleatly removed. The removal of the e-cig at the end of 12 weeks will also disqualify the test subject from using the e-cig without nicotine in times of need over the following 6 month period.

    The beauty of the e-cig is that even after quitting the nicotine people can still use the device without nicotine in times of need without returning to cigarettes or addictive substances and that is why they have such a unique place in the market.

    The terms of this study do not take this into account and IMHO set the participants up for failure as their only choices are to obstain from tobacco, NRTs and e-cigs OR to return to smoking. Under these circmstances my guess is e-cigs will prove to be no-more beneficial than NRT products and simply prove the health departments point that e-cigs are no more effective than current NRT products, they do not offer anything new to the market and are therefore an unnessesary and an unwelcome introduction to the current market.

    While I applaud testing I find it hard not to veiw this study as heavily biased against the e-cig as it compleatly ignores the fact that the e-cig offers something that no exisiting NRT product does, and that is a FAILSAFE in times of need without returning to cigarettes or addictive substances.
    You are forgetting one thing GP. There are not any restrictions on anything other than the nicotine. Personal Vapourisers sans nicotine need no approval nor evaluation.
    Current Vape: Variable Wattage mod, EPM Boge tanks, Something Fruity

  8. #8
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    Quote Originally Posted by Sik View Post
    You are forgetting one thing GP. There are not any restrictions on anything other than the nicotine. Personal Vapourisers sans nicotine need no approval nor evaluation.
    Very true Sik, but it would appear this test is to see if the nicotine in e-cigs is warranted/makes any difference and to assess the e-cigs effectiveness against existing NRT products to see if e-cigs qualify as a valid method of NRT. For the parameters of this study the test subject only gets to use one of the 3 given methods for first 12 weeks ONLY then they go cold turkey for the following 6 months. This test under these circumstance will only prove the health departments point that the use of nicotine in e-cigs is not warranted and provides no more benifits to the quitter than existing NRT products. Further more the results will then be be sited by our health department to support their ban on liquid nicotine and prove the heath departments point that e-cigs offer nothing new or more effective than any NRT product on the market making them an unwarranted addition. This test ignores the fail safe of nicotine free e-cig use over the longer term in times of need/weakness that can assists in continued abstinence from tobacco/nicotine use after weaning off nicotine, which is a unique feature unparalleled by any other approved NRT product.
    Last edited by GirlyPantz; 25-05-11 at 05:25 PM.

  9. #9
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    Quote Originally Posted by GirlyPantz View Post
    Very true Sik, but it would appear this test is to see if the nicotine in e-cigs is warrented/makes any difference and to assess the e-cigs effectiveness against existing NRT products. For the parameters of this study the test subject only gets to use one of the 3 given methods for first 12 weeks ONLY then they go cold turkey for the following 6 months. This test under these circumstance will only prove the health departments point that the use of nicotine in e-cigs is not warrented and will be used to support the ban on liquid nicotine.
    They dont use those criteria on the current NRT's though so its hardly a realistic comparision surely.
    confusing....

  10. #10
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    I might just have to take back what I said about New Zealand in light of this:

    Carrots instead of smokes in NZ prisons

 

 

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